However, systemic, flu-like symptoms such as fatigue, myalgia, fever and headache have also been associated with imiquimod 5% use [95, [103] [104] [105]
Imiquimod is an immune response enhancer that induces production of interferon and several other cytokines
5 mg Aldara is smeared onto the Request PDF | Systemic reactions to imiquimod (Aldara) | Contrary to what The Medical Letter said on May 24, 2004, the topical drug imiquimod (Aldara) which is used to treat actinic keratosis and ear congestion
redness of the skin (severe) scaling
The most clinically serious adverse event reported following multiple oral imiquimod doses of >200 mg (equivalent to imiquimod content of >16 packets) was hypotension, which
Treatment was given for a period of 16 weeks
Patients may experience flu-like systemic signs and symptoms during treatment with imiquimod cream
The half-life of topical imiquimod at the treatment site is between 21 and 27 h, with little variation between application to the face, scalp or hands
J Am Acad Dermatol
We have previously used Imiquimod (IMQ) is an immune response modifier that induces immune reactions and the secretion of cytokines reulting in antiviral and antiinflammatory responses
Some subjects also reported systemic reactions
treatment due to systemic drug-related adverse reactions, none of which were severe